Defining how pluripotency is controlled by live imaging of RNA dynamics. This project will use real-time live imaging techniques to study how pluripotent cells localise RNAs in single cells of living

Description

Defining how pluripotency is controlled by live imaging of RNA dynamics. This project will use real-time live imaging techniques to study how pluripotent cells localise RNAs in single cells of living embryos to maintain their capacity to produce any type of specialised cell of the body. This work is anticipated to reveal definitive RNAs and proteins that drive pluripotency, and lead a paradigm shift in our approach to study pluripotency and embryogenesis using less invasive molecular and cellular techniques. The benefits of this research include new knowledge on animal reproductive traits leveraged to optimise the breeding of endangered species and livestock, as well as findings that will support work into Australia’s decreasing fertility rates and in pluripotency in adult tissue regeneration as Australians age.. Scheme: Discovery Projects. Field: 3109 - Zoology. Lead: A/Prof Jennifer Zenker