A platform for protein design and evolution in mammalian cells. This project combines protein evolution and machine learning to develop tools for designing and optimising proteins with new or improved

Description

A platform for protein design and evolution in mammalian cells. This project combines protein evolution and machine learning to develop tools for designing and optimising proteins with new or improved functions. We will establish a state of the art platform for protein evolution in mammalian cells, enabling the creation of novel proteins for gene regulation and biotechnological applications. Simultaneously, we will harness evolutionary insights to train efficient and accurate machine learning models for protein design. By integrating these approaches, we aim to overcome limitations in biomolecular engineering, making it faster, more precise, and accessible for real-world applications. This research will benefit synthetic biology by enabling the production of tailored proteins for diverse challenges.. Scheme: Discovery Projects. Field: 3101 - Biochemistry and Cell Biology. Lead: Prof Colin Jackson