Uncovering heme regulation, handling & transport in mitochondria. Life is sustained through many important biochemical reactions that can extract energy and build new molecules for the cell to grow. I

Description

Uncovering heme regulation, handling & transport in mitochondria. Life is sustained through many important biochemical reactions that can extract energy and build new molecules for the cell to grow. Important to many of these reactions is a metal-containing molecule called heme. Heme is made in the mitochondria and it is still unclear what the consequences are when there is too much or too little of this molecule. Additionally, we do not know how heme gets out of mitochondria once made. This project addresses these two important questions using new and complementary approaches. Staff and students trained during this project will develop highly sought-after skills that will showcase Australian innovation and research capabilities and lead to new insights that will benefit agriculture and the life sciences.. Scheme: Discovery Projects. Field: 3101 - Biochemistry and Cell Biology. Lead: Dr Luke Formosa