Site-specific protein functionalisation at diselenides via photocatalysis . This project aims to develop a new photocatalytic reaction for the on demand functionalisation of proteins. The synthetic me

Description

Site-specific protein functionalisation at diselenides via photocatalysis . This project aims to develop a new photocatalytic reaction for the on demand functionalisation of proteins. The synthetic methodology will solve a major technological gap in the field by enabling efficient access to proteins with defined modifications at specific locations. Functionalised proteins generated in the project will underpin a detailed understanding of how specific modifications influence the structure and function of several important proteins. The project will generate significant new knowledge in the fields of chemistry and biology and will foster interdisciplinary collaboration, nationally and internationally. The breakthrough technology also has the potential to benefit Australia’s biotechnology sector.. Scheme: Discovery Projects. Field: 3404 - Medicinal and Biomolecular Chemistry. Lead: Prof Richard Payne