First Real-Time Assessment of the Mitochondrial Membrane Potential in Cells. Mitochondria are the powerhouses of organisms, supplying 95% of the energy required for cell metabolism. The mitochondrial

Description

First Real-Time Assessment of the Mitochondrial Membrane Potential in Cells. Mitochondria are the powerhouses of organisms, supplying 95% of the energy required for cell metabolism. The mitochondrial membrane potential (MMP) is pivotal in regulating ATP synthesis and cellular respiration. This project aims to develop the first tool for high-resolution, real-time measurement of MMP in living cells by combining cutting-edge innovations in chemical biology and sub-cellular targeting. This technology has the potential to significantly advance our understanding of mitochondrial health and dysfunction in a range of fields from ageing to agriculture. Benefits include the development of new research tools, diagnostic assays, and future contributions to therapeutic strategies for conditions linked to mitochondrial activity.. Scheme: Discovery Projects. Field: 3402 - Inorganic Chemistry. Lead: Prof Louis Rendina