Cellular targets and mechanisms of action of C. barnesi Irukandji venom. This project investigates the cellular targets and mechanisms of action of Carukia barnesi venom, the cause of Irukandji Syndro

Description

Cellular targets and mechanisms of action of C. barnesi Irukandji venom. This project investigates the cellular targets and mechanisms of action of Carukia barnesi venom, the cause of Irukandji Syndrome, a life-threatening condition linked to severe pain and autonomic dysfunction. With warming waters expanding the habitat of C. barnesi toward populated areas, understanding its venom is crucial. Using cutting-edge functional genomic and CRISPR screening technologies, we aim to identify bioactive peptides in the venom and their mammalian targets. This globally unique research combines expertise in venom biology, genomics, and toxin biology to address a critical knowledge gap, advancing venom science and informing strategies to manage and mitigate the impacts of Irukandji Syndrome.. Scheme: Discovery Projects. Field: 4103 - Environmental Biotechnology. Lead: Prof Graham Neely