Elucidating the molecular mechanisms of dual function transporter/channels. This project aims to understand how a membrane protein that transports chemical messengers in the brain functions and how it

Description

Elucidating the molecular mechanisms of dual function transporter/channels. This project aims to understand how a membrane protein that transports chemical messengers in the brain functions and how it is influenced by the membrane in which it is embedded. Cells from all life forms have a lipid membrane that separates them from their external environment. These membranes contain proteins that control the movements of molecules into and out of cells and are vital for a plethora of physiological processes including cell-to-cell communication. The outcomes of this study will include new knowledge of this process and chemical modifiers of this transport protein. This project will benefit structural biology and biophysics training and may lead to the development of novel compounds that can be used to explore function. . Scheme: ARC Future Fellowships. Field: 3101 - Biochemistry and Cell Biology. Lead: Prof Renae Ryan