Non-Canonical Amino Acids for Protein Analysis in vitro and in Cells. This interdisciplinary project aims to develop new tools for the rapid and easy investigation of proteins at low concentrations an

Description

Non-Canonical Amino Acids for Protein Analysis in vitro and in Cells. This interdisciplinary project aims to develop new tools for the rapid and easy investigation of proteins at low concentrations and in their natural environments, such as within cells. By combining innovative biochemistry, modern spectroscopy, and AI-based molecular modelling, the project will explore the structure and dynamics of proteins as well as protein-ligand interactions. The goal is to create new integrative approaches and test them on established drug targets. Expected outcomes include tools that quickly provide insights into how drugs interact with their targets in cellular environments, thus assisting researchers in their future discoveries in health and life sciences and supporting the growth of Australia's biotechnology sector.. Scheme: Discovery Projects. Field: 3101 - Biochemistry and Cell Biology. Lead: Prof Thomas Huber