Neural mechanisms driving dynamic responses to fatigue. Fatigue is pervasive, yet individuals vary widely in their response to it – some people are able to continue investing effort in spite of their

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Neural mechanisms driving dynamic responses to fatigue. Fatigue is pervasive, yet individuals vary widely in their response to it – some people are able to continue investing effort in spite of their fatigue, whereas others choose to rest. The neurobiological principles that govern when and why people decide to work versus rest remain poorly understood. This research will combine a novel behavioural paradigm with computational models of behaviour, pharmacological manipulations, functional neuroimaging and non-invasive brain stimulation to understand how we dynamically adapt our behaviour in response to the ebbs and flows of fatigue. Ultimately, this project will lead to a comprehensive neurobiological framework that is able to explain, predict and optimise behaviour as fatigue evolves over time.. Scheme: Discovery Projects. Field: 5202 - Biological Psychology. Lead: A/Prof Trevor Chong