Integrative neuroscience of perceptual decision-making. The transformation of sensory input into goal-directed action is central to cognitive function and is known as perceptual decision-making. This

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Integrative neuroscience of perceptual decision-making. The transformation of sensory input into goal-directed action is central to cognitive function and is known as perceptual decision-making. This project will forge links between scales (network to synapse) and species (human to rodent) to understand how the dynamic equilibrium between excitatory and inhibitory inputs in the brain (known as E/I balance) shape fundamental properties of decision-making, such as evidence accumulation. We will employ a common behavioural paradigm across both species and leverage cutting-edge techniques in humans (MRS; EEG, computational modelling) and rodents (optogenetics, EEG, computational modelling). We will reveal the causal mechanisms by which manipulations of E/I balance impact evidence accumulation.. Scheme: Discovery Projects. Field: 5202 - Biological Psychology. Lead: Prof Mark Bellgrove