Reprogrammed cyclic peptides as next-generation targeted protein degraders. This project aims to pioneer a technology for the discovery of bioactive peptides called PEPTACs. These innovative circular

Description

Reprogrammed cyclic peptides as next-generation targeted protein degraders. This project aims to pioneer a technology for the discovery of bioactive peptides called PEPTACs. These innovative circular peptide molecules will be capable of interacting with two proteins simultaneously, leading to the targeted elimination of specific proteins within a cell. Expected outcomes include the delivery of a transformative method for the rapid discovery of bioactive molecules, significant advances in artificial intelligence for medicinal chemistry applications and the training of industry-ready early career researchers. This will provide significant benefits to Australia including strengthening our growing pharmaceutical and biotechnology sectors.. Scheme: Linkage Projects. Field: 3404 - Medicinal and Biomolecular Chemistry. Lead: Prof Richard Payne