A molecular platform for design and production of next-generation peptides. This project aims to use novel cystine-rich peptides as ultra-stable miniature biologics to solve the problem of a lack of s

Description

A molecular platform for design and production of next-generation peptides. This project aims to use novel cystine-rich peptides as ultra-stable miniature biologics to solve the problem of a lack of specificity and stability of many existing diagnostic agents. This project expects to generate cutting-edge molecular methods for engineering of these next-generation molecules to bind specific target proteins while retaining their chemical structures, new chemical ways for precise late-stage functionalisation with a metal cage, and new biochemical methods for scalable and sustainable manufacturing. Development of this molecular platform should strengthen a highly successful collaboration with our Australian partner and position them for future development of molecules for the targeted delivery of radiation.. Scheme: Linkage Projects. Field: 3404 - Medicinal and Biomolecular Chemistry. Lead: A/Prof Conan Wang