G protein-coupled receptor Response Mechanisms to Environmental Pollutants. This project aims to elucidate how plastic pollutants interact with membrane receptors, specifically two critical cellular s

Description

G protein-coupled receptor Response Mechanisms to Environmental Pollutants. This project aims to elucidate how plastic pollutants interact with membrane receptors, specifically two critical cellular sensors: adenosine A1 receptors and G protein-coupled estrogen receptors. It integrates molecular biology, analytical pharmacology, computational modelling, and artificial intelligence. The anticipated outcome is a comprehensive insight into ligand-receptor binding, trafficking, signalling and molecular interactions of these plastic pollutants, which have broad implications for public health and environmental policy. This research could potentially lead to the development of safer and more effective strategies for managing and mitigating the impact of environmental pollutants on human health and ecosystems.. Scheme: Discovery Early Career Researcher Award. Field: 3101 - Biochemistry and Cell Biology. Lead: Dr Anh Nguyen